Effects of androgens on cardiovascular remodeling
نویسندگان
چکیده
منابع مشابه
Cardiovascular Effects of Androgens
Androgens are the male sex hormones responsible for development of the male reproductive system. Testosterone is the main androgen, however, other circulating androgens also exist; these are dehydroepiandrosterone, androstenedione and androstenediol. In some tissues, testosterone can be converted to dihydrotestosterone by action of 5┙-reductase. Testosterone is also found in females, but at muc...
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PURPOSE OF REVIEW There is increasing interest in age-related changes in sex hormone levels as a potentially treatable cause of ill-health in men. Relationships between androgens and cardiovascular disease will be discussed, with particular attention to more recently published research. RECENT FINDINGS In middle-aged and older men, lower testosterone levels are associated with insulin resista...
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15 صفحه اولAndrogens and cardiovascular disease.
Globally, cardiovascular disease will continue causing most human deaths for the foreseeable future. The consistent gender gap in life span of approximately 5.6 yr in all advanced economies must derive from gender differences in age-specific cardiovascular death rates, which rise steeply in parallel for both genders but 5-10 yr earlier in men. The lack of inflection point at modal age of menopa...
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ژورنال
عنوان ژورنال: Journal of Endocrinology
سال: 2012
ISSN: 0022-0795,1479-6805
DOI: 10.1530/joe-12-0126